The WD40-repeat protein WDR-48 promotes the stability of the deubiquitinating enzyme USP-46 by inhibiting its ubiquitination and degradation
M. Hodul, R. Ganji, C. L. Dahlberg, M. Raman, P. Juo
This study shows that WDR-48 stabilizes USP-46 by preventing its ubiquitination and degradation, highlighting a conserved mechanism for regulating DUB availability.
bioRxiv · Jun 21, 2019Biochemistry