Author

C. Le Coz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

N. Romberg· 2 shared A. Arsenijevic· 1 shared A. Bar-Or· 1 shared A. V. C. Knox· 1 shared C. Spanos· 1 shared D. A. Espinoza· 1 shared D. A. Oldridge· 1 shared D. Pueschl· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

N. Romberg

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Author profile →

3 papers

Recent·Most cited

SUMOylation regulates Lem2 function in centromere clustering and silencing

J. Strachan, O. Leidecker, C. Spanos, C. Le Coz, E. Chapman, A. Arsenijevic, H. Zhang, N. Zhao, E. H. Bayne

The paper shows that SUMOylation of Lem2 in fission yeast affects centromere clustering and silencing by modulating its interactions with partner proteins.

bioRxiv · Nov 2, 2022Cell Biology

Human T follicular helper clones seed the germinal center-resident regulatory pool

C. Le Coz, D. A. Oldridge, R. S. Herati, N. De Luna, J. Garifallou, E. C. Cabrera, J. P. Belman, D. Pueschl, L. V. Silva, A. V. C. Knox, S. Yoon, K. B. Zur, S. D. Handler, H. Hakonarson, E. J. Wherry, , N. Romberg

The paper identifies human Tfr cells as either Treg-derived (nTfr) or Tfh-derived (iTfr) clones, with distinct functional and spatial characteristics.

bioRxiv · Oct 26, 2022Immunology

Distinct stage-specific transcriptional states of B cells in human tonsillar tissue.

D. A. Espinoza, C. Le Coz, N. Romberg, A. Bar-Or, R. Li

The paper uses single-cell RNA-seq to identify distinct B-cell activation and maturation states in human tonsillar tissue, including a novel chemokine-expressing population and regulatory mechanisms driving GC-to-ASC transition.

bioRxiv · Aug 17, 2021Immunology