Author

L. V. Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

E. J. Wherry· 2 shared R. S. Herati· 2 shared A. Kossenkov· 1 shared A. Muselman· 1 shared A. V. C. Knox· 1 shared B. Bengsch· 1 shared C. Alanio· 1 shared C. Le Coz· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

E. J. Wherry

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Author profile →

2 papers

Recent·Most cited

Human T follicular helper clones seed the germinal center-resident regulatory pool

C. Le Coz, D. A. Oldridge, R. S. Herati, N. De Luna, J. Garifallou, E. C. Cabrera, J. P. Belman, D. Pueschl, L. V. Silva, A. V. C. Knox, S. Yoon, K. B. Zur, S. D. Handler, H. Hakonarson, E. J. Wherry, , N. Romberg

The paper identifies human Tfr cells as either Treg-derived (nTfr) or Tfh-derived (iTfr) clones, with distinct functional and spatial characteristics.

bioRxiv · Oct 26, 2022Immunology

Vaccine-induced ICOS+CD38+ cTfh are sensitive biosensors of age-related changes in inflammatory pathways

R. S. Herati, L. V. Silva, L. A. Vella, A. Muselman, C. Alanio, B. Bengsch, R. Kurupati, S. Kannan, S. Manne, A. Kossenkov, D. Canaday, S. Doyle, H. Ertl, K. Schmader, E. J. Wherry

The paper uses transcriptional profiling to show that vaccine-induced ICOS+CD38+ cTfh cells in elderly show inflammation-related gene signatures and age-associated biological changes.

bioRxiv · Jul 24, 2019 · PreprintImmunology