Author

C. Le Guiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Bourdon· 2 shared O. Adjali· 2 shared A. Galy· 1 shared A. Kuony· 1 shared A. Mendes· 1 shared B. Gautier· 1 shared C. Audrain· 1 shared C. Delettre· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPathology

A. Bourdon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dystrophin deficiency impairs cell junction formation during embryonic myogenesis

E. Mozin, E. Massourides, V. Mournetas, C. Lievre, A. Bourdon, D. L. Jackson, J. S. Packer, J. Seong, C. Trapnell, C. Le Guiner, O. Adjali, C. Pinset, D. L. Mack, J.-B. Dupont

This study shows that dystrophin deficiency disrupts cell junction formation during embryonic myogenesis in human pluripotent stem cells.

bioRxiv · Dec 5, 2023 · PreprintPathology

Mannose-coupled AAV2: a second generation AAV vector for increased retinal gene therapy efficiency

M. MEVEL, V. Pichard, M. Bouzelha, D. Alvarez-Dorta, P.-A. Lalys, N. Provost, M. Allais, A. Mendes, E. Landagaray, J.-B. Ducloyer, A. Galy, N. Brument, G. M. Lefevre, S. G. Gouin, C. Isiegas, , O. Adjali

This study develops a modified AAV vector with increased transduction efficiency in retinas of rats and nonhuman primates by covalently attaching mannose ligands.

bioRxiv · Dec 1, 2022Bioengineering

AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modification

B. Gautier, L. Meneux, N. Feret, C. Audrain, L. Hudecek, A. Kuony, A. Bourdon, C. Le Guiner, V. Blouin, C. Delettre, F. Michon

This study uses AAV2/9 gene transfer to modify tear film composition in mice, showing long-term secretion of nerve growth factor to support corneal health.

bioRxiv · Feb 16, 2022Physiology