Transient cell-in-cell formation underlies tumor resistance to immunotherapy
A. Gutwillig, N. Santana-Magal, L. Farhat-Younis, D. Rasoulouniriana, A. Madi, C. Luxenburg, J. Cohen, K. Padmanabhan, N. Shomron, G. Shapira, M. Feinmesser, O. Zlotnik, R. Debets, N. E. Reticker-Flynn, P. Rider, Y. Carmi
This study identifies transient cell-in-cell formations as a mechanism enabling tumor resistance to immunotherapy, showing they protect tumor cells from immune and chemotherapy attacks.
bioRxiv · Sep 10, 2020 · PreprintImmunology