Structural determinants of persulfide-sensing specificity in a dithiol-based transcriptional regulator
D. A. Capdevila, B. J. C. Walsh, Y. Zhang, C. M. Dietrich, G. Gonzalez-Gutierrez, D. P. Giedroc
The paper identifies structural determinants of persulfide-sensing specificity in SqrR, showing that structural frustration of the disulfide form enhances tetrasulfide bridge formation and persulfide selectivity.
bioRxiv · Mar 22, 2020Biochemistry