A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation
P. M. Laughlin, K. Young, J. C.-Y. Wang, G. Gonzalez-Gutierrez, A. Zlotnick
This study investigates how the ratio of nucleic acid to SARS-CoV-2 N-protein affects liquid-liquid phase separation (LLPS) and finds that a 1:1 ratio maximizes condensate formation.
bioRxiv · Apr 10, 2024Biochemistry