Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates
L. M. Seenappa, A. Jakubowski, M. P. Steinbuck, E. Palmer, C. M. Haqq, C. Carter, J. Fontenot, F. Villinger, L. K. McNeil, P. C. DeMuth
This study evaluates an AMP-CpG adjuvant in combination with SARS-CoV-2 RBD as a subunit vaccine, showing enhanced T cell and cross-reactive antibody responses in mice and NHPs.
bioRxiv · May 19, 2022 · PreprintImmunology