Author

F. Villinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:non-human primate· 5 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

B. Pulendran· 2 shared J. Fontenot· 2 shared K. Rogers· 2 shared P. S. Arunachalam· 2 shared A. B. Ward· 1 shared A. Blackstone· 1 shared A. Byrd· 1 shared A. C. Walls· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

B. Pulendran

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates

M. Buckley, M. Arainga, L. Maiorino, I. S. Pires, B. J. Kim, K. Kaczmarek Michaels, J. Dye, K. Qureshi, Y. Zhang, H. Mak, J. M. Steichen, W. R. Schief, F. Villinger, D. J. Irvine

This study visualizes lipid nanoparticle trafficking in non-human primates using PET imaging, showing distribution to muscle and draining lymph nodes with uptake by antigen-presenting cells.

bioRxiv · Jun 21, 2024Bioengineering

Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.

A. N. Nelson, X. Shen, S. Venkatayogi, S. Zhang, G. Ozorowski, M. Dennis, L. M. Sewall, E. Milligan, D. Davis, K. Cross, Y. Chen, J. van Schooten, J. Eudaily, J. Isaac, S. Memon, , S. R. Permar

This study shows that a multi-dose immunization with germline-targeting SOSIP vaccines induces precursor broadly neutralizing antibodies in infant macaques, similar to adult responses.

bioRxiv · Nov 7, 2023 · PreprintImmunology

Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates

L. M. Seenappa, A. Jakubowski, M. P. Steinbuck, E. Palmer, C. M. Haqq, C. Carter, J. Fontenot, F. Villinger, L. K. McNeil, P. C. DeMuth

This study evaluates an AMP-CpG adjuvant in combination with SARS-CoV-2 RBD as a subunit vaccine, showing enhanced T cell and cross-reactive antibody responses in mice and NHPs.

bioRxiv · May 19, 2022 · PreprintImmunology

Safety, immunogenicity and protection provided by unadjuvanted and adjuvanted formulations of recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in non-human primates

S. Pillet, P. S. Arunachalam, G. Andreani, N. Golden, J. Fontenot, P. Aye, K. Röltgen, G. Lehmick, C. Dube, P. Gobeil, S. Trepanier, N. Charland, M.-A. D'Aoust, K. Russell-Lodrigue, R. V. Blair, , N. Landry

This study evaluates the safety and immunogenicity of a plant-derived VLP vaccine against SARS-CoV-2 in non-human primates, finding that AS03 adjuvanted vaccine provides better protection and immune response.

bioRxiv · May 15, 2021Immunology

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

A. C. Walls, M. C. Miranda, M. N. Pham, A. Schaefer, A. Greaney, P. S. Arunachalam, M.-J. Navarro, M. A. Tortorici, K. Rogers, M. A. O'Connor, L. Shireff, D. E. Ferrell, N. Brunette, E. Kepl, J. E. Bowen, , Veesler

This study shows that a SARS-CoV-2 RBD nanoparticle vaccine protects against SARS-CoV-2 and related sarbecoviruses, including variants, in mice and non-human primates.

bioRxiv · Mar 15, 2021Immunology

Age associated microbiome modulation and its association with systemic inflammation in a Rhesus Macaque Model

S. Pallikuth, K. B. Russell, T. Sirupangi, R. Mendez, D. K. Kvistad, R. Pahwa, F. Villinger, S. Banerjee, S. Pahwa

This study examines age-related changes in the microbiome and systemic inflammation in Rhesus macaques, finding significant differences in microbial composition and metabolite profiles between young and old animals.

bioRxiv · Feb 11, 2020 · PreprintMicrobiology