Microarray screening reveals a non-conventional SUMO-binding mode linked to DNA repair by non-homologous end-joining
M. J. Cabello-Lobato, M. Jenner, C. M. Loch, S. P. Jackson, Q. Wu, M. J. Cliff, C. K. Schmidt
The paper identifies non-conventional SUMO2-binding modules on XRCC4 through microarray screening and structural analysis, revealing their role in DNA repair and implications for cancer and gene editing.
bioRxiv · Jan 20, 2021Biochemistry