Author

S. P. Jackson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Hill· 1 shared A. Jassim· 1 shared A. Patrizi· 1 shared A. R. Wanders· 1 shared A. Regev· 1 shared A. Serrano-Benitez· 1 shared B. V. Nimmervoll· 1 shared C. J. Blum· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Hill

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Natural language processing charts transcriptome evolution to design combination cancer therapies

A. Jassim, B. V. Nimmervoll, S. Terranova, E. Nathan, K. E. Masih, L. Ruff, M. Duarte, E. Cooper, L. P. Hu, G. Katyal, M. Akhbari, R. J. Gilbertson, C. Terhune, G. Balmus, S. P. Jackson, , R. J. Gilbertson

This paper introduces RECODR, a computational pipeline that tracks transcriptome changes in cancer development and treatment to predict resistance mechanisms and design effective therapies.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology

The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity

C. J. Carnie, M. J. Gotz, C. S. Palma-Chaundler, P. Weickert, A. R. Wanders, A. Serrano-Benitez, H.-Y. Li, V. Gupta, C. J. Blum, M. Sczaniecka-Clift, G. Zagnoli-Vieira, G. D'Alessandro, S. L. Richards, N. Gueorguieva, P. Beli, , S. P. Jackson

This study identifies DCTD and TOPORS as key factors in decitabine cytotoxicity by showing their roles in DPC formation and repair.

bioRxiv · Dec 21, 2023Cell Biology

Development of supramolecular anticoagulants with on-demand reversibility

M. Dockerill, D. J. Ford, S. Angerani, I. Alwis, J. Ripoll-Rozada, R. E. Smythe, J. S. T. Liu, P. J. Barbosa Pereira, S. P. Jackson, R. J. Payne, N. Winssinger

This paper develops supramolecular anticoagulants that can be reversed on demand using a PNA antidote, demonstrating potent in vitro and in vivo anticoagulant activity.

bioRxiv · Nov 12, 2023Biochemistry

Microarray screening reveals a non-conventional SUMO-binding mode linked to DNA repair by non-homologous end-joining

M. J. Cabello-Lobato, M. Jenner, C. M. Loch, S. P. Jackson, Q. Wu, M. J. Cliff, C. K. Schmidt

The paper identifies non-conventional SUMO2-binding modules on XRCC4 through microarray screening and structural analysis, revealing their role in DNA repair and implications for cancer and gene editing.

bioRxiv · Jan 20, 2021Biochemistry