C. M. Mageeney

Niche exclusion of a lung pathogen in mice with designed probiotic communities

This study shows that probiotic communities can prevent Burkholderia thailandensis infection in mice by reducing niche overlap with the pathogen.

Identification of a new antiphage system in Mycobacterium phage Butters

This paper identifies a new antiphage system in Mycobacterium phage Butters, showing that gp57r inhibits infection by Island3 and other phages through a HEPN domain, with implications for phage therapy.

Development of Potent and Effective Synthetic SARS-CoV-2 Neutralizing Nanobodies

This paper identifies and characterizes potent SARS-CoV-2 neutralizing nanobodies that block viral entry and show efficacy in vivo.

Mycobacterium phage Butters-encoded proteins contribute to host defense against viral attack

The paper identifies a novel prophage-encoded defense mechanism in Cluster N mycobacteriophages, showing that genes 30 and 31 form a two-component system that partially protects against heterotypic phage infection.

Computationally-guided technology platform for on-demand production of diversified therapeutic phage cocktails

This paper develops a computational platform to produce customized phage cocktails targeting antibiotic-resistant bacteria, demonstrating efficacy against Pseudomonas aeruginosa.