Author

K. P. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Sinha· 2 shared C. M. Mageeney· 2 shared S. S. Branda· 2 shared A. B. Rokes· 1 shared A. M. E. Phillips· 1 shared A. P. Arkin· 1 shared B. Bowman· 1 shared B. Weissman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

A. Sinha

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Niche exclusion of a lung pathogen in mice with designed probiotic communities

K. E. Hern, A. M. E. Phillips, C. M. Mageeney, K. P. Williams, A. Sinha, H. K. Carlson, K. Poorey, N. M. Collette, S. S. Branda, A. P. Arkin

This study shows that probiotic communities can prevent Burkholderia thailandensis infection in mice by reducing niche overlap with the pathogen.

bioRxiv · Feb 2, 2024Microbiology

Small Molecule Screen Identifies Pyrimethamine as an Inhibitor of NRF2-driven Esophageal Hyperplasia

C. Paiboonrungruang, Z. Xiong, D. Lamson, Y. Li, B. Bowman, J. Chembo, C. Huang, J. Li, E. W. Livingston, J. E. Frank, V. Chen, Y. Li, B. Weissman, H. Yuan, K. P. Williams, , X. Chen

This study identifies pyrimethamine as an NRF2 inhibitor that suppresses esophageal hyperplasia in a mouse model and shows potential for clinical use in NRF2-high ESCC.

Redox Biology · Nov 1, 2023Peer-reviewedCancer Biology

Computationally-guided technology platform for on-demand production of diversified therapeutic phage cocktails

C. M. Mageeney, A. Sinha, R. A. Mosesso, D. L. Medlin, B. Y. Lau, A. B. Rokes, T. W. Lane, S. S. Branda, K. P. Williams

This paper develops a computational platform to produce customized phage cocktails targeting antibiotic-resistant bacteria, demonstrating efficacy against Pseudomonas aeruginosa.

bioRxiv · Jan 26, 2020 · PreprintMicrobiology