Author

C. M. Spruit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

R. P. de Vries· 2 shared A. Grawe· 1 shared B. Qiu· 1 shared G.-J. Boons· 1 shared I. R. Sweet· 1 shared J. Snijder· 1 shared M. J. Damen· 1 shared M. Merkx· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

R. P. de Vries

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2 papers

Recent·Most cited

Bioluminescent detection of viral surface proteins using branched multivalent protein switches

A. Grawe, C. M. Spruit, R. P. de Vries, M. Merkx

This paper introduces a modular bioluminescent sensor platform (dark-LUX) for detecting viral surface proteins using multivalent binding domains and NanoBiT technology, demonstrating its application with influenza A virus proteins.

bioRxiv · Sep 22, 2023Biochemistry

Contemporary human H3N2 influenza A viruses require a low threshold of suitable glycan receptors for efficient infection

C. M. Spruit, I. R. Sweet, T. Bestebroer, P. Lexmond, B. Qiu, M. J. Damen, R. A. Fouchier, J. Snijder, S. Herfst, G.-J. Boons, R. P. de Vries

This study shows that recent H3N2 influenza A viruses require a low threshold of glycan receptors for efficient infection, and increasing receptor numbers beyond this threshold does not improve infection efficiency.

bioRxiv · Nov 16, 2022Microbiology