Proteinase-Activated Receptor 4 (PAR4) Activation Triggers Cell Membrane Blebbing through RhoA and β-arrestin
C. M. Vanderboor, P. E. Thibeault, K. C. Nixon, R. Gros, J. M. Kramer, R. Ramachandran
This study identifies that PAR4 activation triggers cell membrane blebbing through RhoA and β-arrestin, revealing biased signaling and transcriptional changes in PAR4-dependent pathways.
bioRxiv · Sep 4, 2019Pharmacology & Toxicology