Author

C. M. Weekley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

M. W. Parker· 2 shared D. F. J. Purcell· 1 shared D. P. Byun· 1 shared E. Yoo· 1 shared H.-R. Kim· 1 shared J. Ivanic· 1 shared J. Ritchie· 1 shared R. Holewinski· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

M. W. Parker

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2 papers

Recent·Most cited

Covalent inhibition by a natural product-inspired latent electrophile

D. P. Byun, J. Ritchie, R. Holewinski, H.-R. Kim, R. Tagirasa, J. Ivanic, C. M. Weekley, M. W. Parker, T. Adresson, E. Yoo

This study evaluates the reactivity and selectivity of 3-bromo-4,5-dihydroxazole electrophiles against human cysteine residues and validates their covalent binding to specific targets.

bioRxiv · Jan 16, 2023Biochemistry

SARS-CoV-2 Spike receptor-binding domain with a G485R mutation in complex with human ACE2

C. M. Weekley, D. F. J. Purcell, M. W. Parker

This study reports the crystal structure of SARS-CoV-2 Spike RBD with a G485R mutation bound to human ACE2, showing structural changes that may affect antigenic escape.

bioRxiv · Mar 16, 2021 · PreprintBiochemistry