PKC-ε Regulates Vesicle Delivery and Focal Exocytosis for Efficient IgG-mediated Phagocytosis
A. E. D'Amico, A. C. Wong, C. M. Zajd, A. Murali, M. Lennartz
This paper identifies PKC-ε's role in vesicle trafficking during IgG-mediated phagocytosis, showing its regulatory domain drives vesicle delivery to phagosomes while catalytic activity is needed for fusion.
bioRxiv · May 7, 2021Immunology