Author

A. C. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Di Francesco· 1 shared A. E. D'Amico· 1 shared A. Freund· 1 shared A. G. Deighan· 1 shared A. Murali· 1 shared A. Raj· 1 shared A. S. Bhatt· 1 shared C. A. Thaiss· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Di Francesco

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice

L. Litichevskiy, M. Considine, J. Gill, V. Shandar, T. O. Cox, H. C. Descamps, K. M. Wright, K. R. Amses, L. Dohnalova, M. J. Liou, M. Tetlak, M. R. Galindo-Fiallos, A. C. Wong, P. Lundgren, J. Kim, , C. A. Thaiss

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

bioRxiv · Nov 28, 2023 · PreprintMicrobiology

PKC-ε Regulates Vesicle Delivery and Focal Exocytosis for Efficient IgG-mediated Phagocytosis

A. E. D'Amico, A. C. Wong, C. M. Zajd, A. Murali, M. Lennartz

This paper identifies PKC-ε's role in vesicle trafficking during IgG-mediated phagocytosis, showing its regulatory domain drives vesicle delivery to phagosomes while catalytic activity is needed for fusion.

bioRxiv · May 7, 2021Immunology

A virion-based assay for glycoprotein thermostability reveals key determinants of filovirus entry and its inhibition

R. H. Bortz, A. C. Wong, M. G. Grodus, H. Recht, M. C. Pulanco, G. Lasso, S. J. Anthony, E. Mittler, R. K. Jangra, K. Chandran

This paper introduces an ELISA-based assay to measure the thermostability of filovirus glycoproteins, revealing how proteolytic cleavage, acid pH, and small-molecule inhibitors affect GP stability and viral entry.

bioRxiv · Feb 25, 2020Microbiology