Identification of Human Immune Cell Subtypes Most Vulnerable to IL-1β-induced Inflammatory Signaling Using Mass Cytometry
H. Kothari, C. M. Williams, C. McSkimming, M. Vigneshwar, E. R. Zunder, C. A. McNamara
This study identifies human immune cell subtypes most responsive to IL-1β using mass cytometry, showing that CCR6+ T cells and CD11c mDCs show strong p-NF-κB activation, which is inhibited by Anakinra.
bioRxiv · Apr 19, 2020Immunology