Author

C. A. McNamara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Shemesh· 2 shared C. C. Hedrick· 2 shared C. P. Durant· 2 shared J. Vallejo· 2 shared K. Ley· 2 shared L. L. Lanier· 2 shared P. Roy· 2 shared R. Gulati· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Shemesh

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4 papers

Recent·Most cited

A protective role for B-1 cells and oxidation-specific epitope IgM in lung fibrosis

J. M. Sturek, R. T. Hannan, A. Upadhye, E. Otoupalova, E. T. Faron, A. A. E. Atya, C. Thomas, V. Johnson, A. Miller, J. C. Garmey, M. D. Burdick, T. H. Barker, A. Kadl, Y. M. Shim, C. A. McNamara

This study shows B-1 cells and IgMOSE reduce lung fibrosis by modulating CXCR4 and Id3, with sIgM-/- mice showing increased mortality from bleomycin injury.

bioRxiv · Apr 11, 2024 · PreprintImmunology

Sex differences in coronary artery disease and diabetes revealed by scRNA-Seq and CITE-Seq of human CD4+ T cells

R. Saigusa, J. Vallejo, R. Gulati, S. S. A. Suthahar, V. Suryawanshi, A. Alimadadi, J. Makings, C. P. Durant, A. Freuchet, P. Roy, Y. Ghosheh, W. Pandori, T. Pattarabanjird, F. Drago, C. A. McNamara, , K. Ley

The paper uses scRNA-Seq and CITE-Seq to analyze CD4+ T cells from patients with and without coronary artery disease and diabetes, identifying sex-specific differences and gene expression patterns.

bioRxiv · May 16, 2022Immunology

Combined protein and transcript single cell RNA sequencing in human peripheral blood mononuclear cells

J. Vallejo, R. Saigusa, R. Gulati, Y. Ghosheh, C. P. Durant, P. Roy, E. Ehinger, T. Pattarabanjird, L. E. Padgett, C. E. Olingy, D. B. Hanna, A. L. Landay, R. P. Tracy, J. M. Lazar, W. J. Mack, , K. Ley

The paper develops combined protein and transcript single-cell RNA sequencing in PBMCs, identifying more cell subsets than traditional methods and showing disease-related transcriptome differences in HIV patients.

bioRxiv · Sep 10, 2020Immunology

Identification of Human Immune Cell Subtypes Most Vulnerable to IL-1β-induced Inflammatory Signaling Using Mass Cytometry

H. Kothari, C. M. Williams, C. McSkimming, M. Vigneshwar, E. R. Zunder, C. A. McNamara

This study identifies human immune cell subtypes most responsive to IL-1β using mass cytometry, showing that CCR6+ T cells and CD11c mDCs show strong p-NF-κB activation, which is inhibited by Anakinra.

bioRxiv · Apr 19, 2020Immunology