Author

C. N. Qi

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

C. L. Mackall· 1 shared C. Lamarche· 1 shared E. W. Weber· 1 shared G. Novakovsky· 1 shared M. K. Levings· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

C. L. Mackall

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1 paper

Recent·Most cited

Repeated stimulation or tonic-signaling chimeric antigen receptors drive regulatory T cell exhaustion

C. Lamarche, G. Novakovsky, C. N. Qi, E. W. Weber, C. L. Mackall, M. K. Levings

This study shows that human regulatory T cells (Tregs) can become exhausted through repetitive stimulation or tonic-signaling CARs, reducing their suppressive function in vivo.

bioRxiv · Jun 27, 2020 · PreprintImmunology