The interplay between Bag-1, Hsp70, and Hsp90 reveals that inhibiting Hsp70 rebinding is essential for Glucocorticoid Receptor activity
E. Kirschke, Z. Roe-Zurz, C. Noddings, D. Agard
This paper investigates the interplay between Bag-1, Hsp70, and Hsp90 in GR reactivation, finding that inhibiting Hsp70 re-binding is critical for GR activity, with Hsp90 playing a unique role in protecting GR from re-inactivation.
bioRxiv · May 3, 2020 · PreprintBiochemistry