The tyrosine phosphatase LAR acts as a receptor of the nidogen-tetanus toxin complex
S. Surana, D. Villarroel-Campos, C. Panzi, S. S. Novoselov, S. Richter, G. Zanotti, G. Schiavo
This study identifies LAR as a receptor for the nidogen-tetanus toxin complex, enabling toxin uptake into motor neurons through fibronectin III domains, independent of its role in TrkB signaling.
bioRxiv · Feb 3, 2023Cell Biology