S. Richter

A conserved transcriptomic model defines metabolic resilience and vulnerability in obesity

The paper constructs a transcriptomic BMI model to identify molecular differences between metabolically healthy and unhealthy obesity in humans and validates it in mice.

Coastal marine mammal conservation using thermal imaging-based detection systems

This study evaluates the effectiveness of thermal imaging systems for detecting smaller marine mammals, specifically killer whales in the Salish Sea.

Remote sensing of emperor penguin abundance and breeding success

This paper develops a phenological model to predict emperor penguin breeding pairs and chicks from sparse satellite data, improving population monitoring in remote areas.

A Tyrosine Phospho-switch within the Longin Domain of VAMP721 modulates SNARE functionality

This study shows that phosphorylation of Y57 in VAMP721 regulates SNARE function by modulating its activity and interaction with cognate partners.

The tyrosine phosphatase LAR acts as a receptor of the nidogen-tetanus toxin complex

This study identifies LAR as a receptor for the nidogen-tetanus toxin complex, enabling toxin uptake into motor neurons through fibronectin III domains, independent of its role in TrkB signaling.

Proteogenomics refines the molecular classification of chronic lymphocytic leukemia

The paper performs a proteogenomic analysis of chronic lymphocytic leukemia, identifies a new poor-prognosis subgroup (ASB-CLL) through proteomic profiling, and links it to clinical outcomes.

Heterodimers of functionally divergent ARF-GEF paralogues prevented by self-interacting dimerisation domain

The paper shows that GNOM and GNL1 ARF-GEFs form homodimers but not heterodimers due to self-interacting dimerisation domains, preventing potentially harmful interactions.

Biologging of emperor penguins - attachment techniques and associated deployment performance

This paper evaluates biologging techniques for emperor penguins, finding that traditional gluing methods harm birds and proposing alternative attachment methods with better deployment success.

GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy

This study shows that glutamine catabolism via GLS regulates redox state, stemness, and autophagy in prostate cancer, affecting radiosensitivity and patient outcomes.

ARF1 dimerization is essential for vesicle trafficking and dependent on activation by ARF-GEF dimers in Arabidopsis

Cryopreservation impairs cytotoxicity and migration of NK cells in 3-D tissue: Implications for cancer immunotherapy

This study shows that cryopreservation reduces NK cell cytotoxicity and motility in 3-D collagen gels, potentially explaining the failure of NK cell therapies for solid tumors.

Infections patterns and fitness effects of Rickettsia and Sodalis symbionts in the green lacewing Chrysoperla carnea

This study identifies Rickettsia and a novel Sodalis strain in green lacewings, showing Sodalis reduces reproductive success while Rickettsia has no significant fitness effect.