Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine
S. Coleon, A. Wiedemann, M. Surenaud, C. Lacabaratz, S. Hue, M. Prague, M. Cervantes-Gonzalez, Z. Wang, J. Ellis, A. Sansoni, C. Pierini, Q. Bardin, M. Fabregue, S. Sharkaoui, P. Hoest, , Y. Levy
This study designs a pan-sarbecovirus vaccine targeting conserved epitopes and shows it induces cross-neutralizing antibodies and T-cell responses in mice and humans.
bioRxiv · Dec 28, 2021Immunology