Author

M. Prague

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Organism:non-human primate· 2 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Wiedemann· 2 shared C. Lacabaratz· 2 shared G. Zurawski· 2 shared M. Alexandre· 2 shared M. Centlivre· 2 shared M. Surenaud· 2 shared N. Dereuddre-bosquet· 2 shared P. Maisonnasse· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Wiedemann

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Impact of variants of concern on SARS-CoV-2 viral dynamics in non-human primates.

A. Marc, R. Marlin, F. Donati, M. Prague, M. Kerioui, C. Herate, M. Alexandre, N. Dereuddre-bosquet, J. Bertrand, V. Contreras, S. Behillil, P. Maisonnasse, S. Van Der Werf, R. Le Grand, J. Guedj

This study examines how SARS-CoV-2 variants of concern affect viral dynamics in non-human primates, finding that most variants escape immune responses, with delta and omicron showing significant differences in viral production rates.

bioRxiv · Nov 9, 2022Microbiology

Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine

S. Coleon, A. Wiedemann, M. Surenaud, C. Lacabaratz, S. Hue, M. Prague, M. Cervantes-Gonzalez, Z. Wang, J. Ellis, A. Sansoni, C. Pierini, Q. Bardin, M. Fabregue, S. Sharkaoui, P. Hoest, , Y. Levy

This study designs a pan-sarbecovirus vaccine targeting conserved epitopes and shows it induces cross-neutralizing antibodies and T-cell responses in mice and humans.

bioRxiv · Dec 28, 2021Immunology

SARS-CoV-2 mechanistic correlates of protection: insight from modelling response to vaccines

M. Alexandre, R. Marlin, M. Prague, C. Severin, N. Kahlaoui, S. Cardinaud, T. Naninck, B. Delache, M. Surenaud, M. Galhaut, N. Dereuddre-Bosquet, M. Cavarelli, P. Maisonnasse, M. Centlivre, C. Lacabaratz, , R. Thiebaut

A mathematical model of viral dynamics is used to identify mechanistic correlates of protection in SARS-CoV-2 vaccines across three non-human primate studies.

bioRxiv · Oct 29, 2021Immunology

Machine learning and mechanistic modeling for prediction of metastatic relapse in breast cancer

C. Nicolo, C. Perier, M. Prague, G. MacGrogan, O. Saut, S. Benzekry

This paper develops a mechanistic model to predict metastatic relapse in breast cancer using clinicopathological data and compares its performance to existing statistical and machine learning methods.

bioRxiv · Mar 26, 2020Cancer Biology