Nanomechanical phenotypes in cMyBP-C mutants that cause hypertrophic cardiomyopathy
C. Suay-Corredera, M. R. Pricolo, D. Velazquez-Carreras, C. Pimenta-Lopes, D. Sanchez-Ortiz, I. Urrutia-Irazabal, S. Vilches, F. Dominguez, G. Frisso, L. Monserrat, P. Garcia-Pavia, E. Herrero-Galan, J. Alegre-Cebollada
This study investigates nanomechanical changes in cMyBP-C mutants linked to hypertrophic cardiomyopathy, finding that pathogenic mutations alter mechanical properties compared to non-pathogenic variants.
bioRxiv · Sep 19, 2020 · PreprintBiophysics