Author

E. Herrero-Galan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. Velazquez-Carreras· 5 shared J. Alegre-Cebollada· 4 shared F. Dominguez· 3 shared P. Garcia-Pavia· 3 shared A. Fernandez-Trasancos· 2 shared C. Suay-Corredera· 2 shared I. Martinez-Martin· 2 shared J. P. Ochoa· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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5 shared papersBiophysics

D. Velazquez-Carreras

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Author profile →

5 papers

Recent·Most cited

Amino acid substitutions hydrophilizing the core of titin domains cause dilated cardiomyopathy

I. Martinez-Martin, A. Crousilles, J. P. Ochoa, D. Velazquez-Carreras, S. A. Mortensen, E. Herrero-Galan, F. Dominguez, P. Garcia-Pavia, D. De Sancho, M. Wilmanns, J. Alegre-Cebollada

The paper identifies amino acid substitutions in titin domains that increase hydrophilicity and cause dilated cardiomyopathy by destabilizing the protein structure.

bioRxiv · Jun 2, 2023Biochemistry

Cell response to extracellular matrix energy dissipation outweighs rigidity sensing

C. Huerta-Lopez, A. Clemente-Manteca, D. Velazquez-Carreras, F. M. Espinosa, J. G. Sanchez, P. Saez, A. Martinez-del-Pozo, M. Garcia-Garcia, S. Martin-Colomo, A. Rodriguez-Blanco, R. Esteban-Gonzalez, F. M. Martin-Zamora, L. Gutierrez-Rus, R. Garcia, P. Roca-Cusachs, , J. Alegre-Cebollada

The paper shows that substrate energy dissipation suppresses YAP mechanosensing more than stiffness cues in cell mechanotransduction.

bioRxiv · Nov 16, 2022Bioengineering

Nanomechanical phenotypes in cMyBP-C mutants that cause hypertrophic cardiomyopathy

C. Suay-Corredera, M. R. Pricolo, D. Velazquez-Carreras, C. Pimenta-Lopes, D. Sanchez-Ortiz, I. Urrutia-Irazabal, S. Vilches, F. Dominguez, G. Frisso, L. Monserrat, P. Garcia-Pavia, E. Herrero-Galan, J. Alegre-Cebollada

This study investigates nanomechanical changes in cMyBP-C mutants linked to hypertrophic cardiomyopathy, finding that pathogenic mutations alter mechanical properties compared to non-pathogenic variants.

bioRxiv · Sep 19, 2020 · PreprintBiophysics

Conserved cysteines in titin sustain the mechanical function of cardiomyocytes

E. Herrero-Galan, F. Dominguez, I. Martinez-Martin, C. Sanchez-Gonzalez, N. Vicente, L. Lalaguna, E. Bonzon-Kulichenko, E. Calvo, E. Gonzalez-Lopez, M. Cobo-Marcos, B. Bornstein, A. Briceno, J. P. Ochoa, J. M. Garcia-Aznar, C. Suay-Corredera, , Aleg

The paper identifies that mutations in conserved titin cysteines disrupt mechanoredox control, leading to dilated cardiomyopathy in humans.

bioRxiv · Sep 5, 2020Physiology

A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues

J. A. Rivas-Pardo, Y. Li, Z. Martonfalvi, R. Tapia-Rojo, A. Unger, A. Fernandez-Trasancos, E. Herrero-Galan, D. Velazquez-Carreras, J. M. Fernandez, W. A. Linke, J. Alegre-Cebollada

The paper introduces a HaloTag-TEV genetic cassette to study protein mechanics in native tissues, showing titin's role in muscle contraction under mechanical forces.

bioRxiv · Jan 17, 2020Biophysics