Therapeutic inhibition of keratinocyte TRPV3 sensory channels by local anesthetic dyclonine
J. Yao, Q. Liu, J. Hu, J. Wang, X. Wei, C. Ping, Y. Gao, C. Xie, Y. Yu, D. Li
This study shows that dyclonine inhibits TRPV3 channels in keratinocytes, rescuing cell death and reducing pruritus in a mouse model.
bioRxiv · Sep 21, 2020Biochemistry