Author

C. S. Murphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Fairfield· 2 shared M. R. Reagan· 2 shared A. Cao· 1 shared A. D'Amico· 1 shared C. A. Garter· 1 shared C. Falank· 1 shared C. G. Gartner· 1 shared C. P. H. Vary· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

H. Fairfield

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Author profile →

2 papers

Recent·Most cited

Inhibition of Acyl-CoA Synthetase Long Chain Isozymes Decreases Multiple Myeloma Cell Proliferation and Causes Mitochondrial Dysfunction

C. S. Murphy, V. E. DeMambro, S. Fadel, H. Fairfield, C. A. Garter, P. Rodriguez, Y.-W. Qiang, C. P. H. Vary, M. R. Reagan

This study shows that inhibiting ACSLs in multiple myeloma cells reduces proliferation and causes mitochondrial dysfunction, suggesting ACSLs as potential therapeutic targets.

bioRxiv · Mar 13, 2024Cancer Biology

The Fatty Acid Binding Protein Family Represents a Novel Target in Multiple Myeloma

M. Farrell, H. Fairfield, M. Karam, A. D'Amico, C. S. Murphy, C. Falank, R. S. Pistofidi, A. Cao, C. R. Marinac, J. A. Dragon, L. McGuinness, C. G. Gartner, R. D. Iorio, E. Jachimowicz, V. DeMambro, , M. R. Reagan

This paper identifies the fatty acid binding protein (FABP) family as a novel therapeutic target in multiple myeloma, showing that FABP inhibition reduces tumor growth and alters key cellular processes.

eLife · Mar 7, 2023Peer-reviewedCancer Biology