P. Rodriguez

An essential role for the Hv1 voltage-gated proton channel in Pseudomonas aeruginosa corneal infection

The paper shows Hv1 is essential for neutrophil control of Pseudomonas aeruginosa corneal infection, despite increased ROS production in Hv1-deficient neutrophils.

Inhibition of Acyl-CoA Synthetase Long Chain Isozymes Decreases Multiple Myeloma Cell Proliferation and Causes Mitochondrial Dysfunction

This study shows that inhibiting ACSLs in multiple myeloma cells reduces proliferation and causes mitochondrial dysfunction, suggesting ACSLs as potential therapeutic targets.

Unveiling Urban Complexity: Integrating OpenStreetMap to enhance representation of fine-scale landscape heterogeneity

This paper enhances global landcover maps by integrating OpenStreetMap data to better represent urban landscape heterogeneity, achieving 89% accuracy in 33 North American cities.

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis

This study creates a mouse model with a selective knockout of the TLQP-21 neuropeptide, revealing its role in temperature-dependent resistance to diet-induced obesity and brown adipose tissue activation.

Identification of trans-AT polyketide clusters in two marine bacteria reveals cryptic similarities between distinct symbiosis factors

This paper identifies trans-AT polyketide gene clusters in two marine bacteria, revealing evolutionary relationships between sesbanimides, glutaramides, and pederin-like pathways.

Virulence strategies of an insect herbivore and oomycete plant pathogen converge on a host E3 SUMO ligase

The paper shows that effectors from an oomycete pathogen and an aphid pest both target the host E3 SUMO ligase SIZ1, with different mechanisms that enhance host susceptibility.

Lokiarchaeon exhibits homoacetogenesis

This paper shows Lokiarchaeon exhibits homoacetogenesis by coupling fermentative H2 production with the Wood-Ljungdahl pathway under anoxic conditions.

An aphid effector promotes barley susceptibility through suppression of defence gene expression

The paper identifies two aphid effectors that enhance barley susceptibility by suppressing defense gene expression, showing species-specific effector function.

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

This study identifies genes in Mycobacterium abscessus that enhance survival in macrophages by analyzing transcriptomes in amoebae and macrophages.