BiochemistrybioRxivPreprint
Kinetics and efficacy of antibody drug conjugates in 3D tumour models
C. S. P. Chaundler, H. Lu, R. Fu…·S. Ghaem-Maghami
This study evaluates ADC efficacy in 3D tumor models, finding that spheroids are less sensitive to ADCs than monolayers, but ADCs can fully penetrate within 24h.
DOI 10.1101/2023.02.14.528517