HIV-1 Vpr-induced DNA damage activates NF-κB through ATM-NEMO independent of cell cycle arrest
C. Sandoval, K. Nisson, O. I. Fregoso
This study shows HIV-1 Vpr induces DNA damage and activates NF-κB through ATM-NEMO, independent of cell cycle arrest, enhancing viral transcription and replication.
bioRxiv · May 23, 2023Microbiology