Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switching and cofilin dependent podosome formation
P. Swiatlowska, B. Sit, Z. Feng, E. Marhuenda, I. Xanthis, S. Zingaro, M. Ward, X. Zhou, Q. Xiao, C. Shanahan, G. Jones, C.-h. Yu, T. Iskratsch
This study shows that matrix stiffness and blood pressure together drive vascular smooth muscle cell phenotypic switching and cofilin-dependent podosome formation in atherosclerosis.
bioRxiv · Dec 27, 2020 · PreprintCell Biology