Author

C. Silacci Fregni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Walls· 2 shared A. De Marco· 2 shared A. Telenti· 2 shared B. Guarino· 2 shared D. Corti· 2 shared D. Pinto· 2 shared E. Cameroni· 2 shared F. Benigni· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. C. Walls

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Extremely potent human monoclonal antibodies for the prophylaxis and therapy of Tetanus

M. Pirazzini, A. Grinzato, D. Corti, S. Barbieri, O. Leka, F. Vallese, M. Tonellato, C. Silacci Fregni, L. Piccoli, E. Kandiah, G. Schiavo, G. Zanotti, A. Lanzavecchia, C. Montecucco

This study identifies two human monoclonal antibodies with high neutralizing activity against tetanus neurotoxin, showing potential for both prophylaxis and therapy.

bioRxiv · May 24, 2021Pathology

Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody

M. A. Tortorici, N. Czudnochowski, T. N. Starr, R. Marzi, A. C. Walls, F. Zatta, J. E. Bowen, S. Jaconi, J. di Iulio, Z. Wang, A. De Marco, S. Zepeda, D. Pinto, Z. Liu, M. Beltramello, , J. Bloom

This paper identifies a human monoclonal antibody that broadly neutralizes SARS-CoV-2 variants and zoonotic sarbecoviruses by targeting a conserved epitope on the spike protein.

bioRxiv · Apr 7, 2021 · PreprintImmunology

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2

M. McCallum, A. De Marco, F. Lempp, M. A. Tortorici, D. Pinto, A. C. Walls, M. Beltramello, A. Chen, Z. Liu, F. Zatta, S. Zepeda, J. di Iulio, J. E. Bowen, M. Montiel-Ruiz, J. Zhou, , D. Veesler

The paper identifies a conserved antigenic supersite on the SARS-CoV-2 N-terminal domain recognized by neutralizing antibodies and shows its vulnerability to mutations in variants.

bioRxiv · Jan 14, 2021Immunology