Solid immersion microscopy readily and inexpensively enables 12 nm resolution on plunge-frozen cells
M. L. Martin-Fernandez, L. Wang, B. Bateman, L. C. Zanetti-Domingues, A. Moores, S. R. Needham, D. Rolfe, S. Astbury, C. Spindloe, M. Darrow, M. Romano, K. Beis, D. Clarke
This paper introduces a low-cost solid immersion lens technique that achieves 12 nm resolution in cryogenic fluorescence microscopy, outperforming more expensive systems.
bioRxiv · Jul 20, 2018 · PreprintBiophysics