Author

S. R. Needham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. S. Woolf· 1 shared B. Davis· 1 shared B. Humphreys· 1 shared B. J. Stewart· 1 shared B. M. Davis· 1 shared C. L. Walsh· 1 shared C. Perera· 1 shared D. A. Long· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPathology

A. S. Woolf

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A unique subset of pericystic endothelium associates with aberrant microvascular remodelling and impaired blood perfusion early in polycystic kidney disease

D. J. Jafree, C. Perera, M. Ball, D. Tolomeo, G. Pomeranz, L. Wilson, B. Davis, W. J. Mason, E. M. Funk, M. Kolatsi-Joannou, R. Polschi, S. Malik, B. J. Stewart, K. L. Price, H. Mitchell, , D. A. Long

The paper identifies a unique pericystic endothelium in ADPKD that contributes to microvascular remodelling and impaired perfusion, suggesting vascular targets for early intervention.

bioRxiv · Mar 3, 2024 · PreprintPathology

The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

R. S. Iyer, S. R. Needham, I. Galdadas, B. M. Davis, S. K. Roberts, R. C. Man, L. C. Zanetti-Domingues, D. T. Clarke, G. O. Fruhwirth, P. J. Parker, D. J. Rolfe, F. L. Gervasio, M. L. Martin-Fernandez

This study identifies how the T766M-EGFR mutation promotes tumor growth by utilizing new oligomer assembly mechanisms in ligand-free EGFR.

bioRxiv · Jun 16, 2023 · PreprintCancer Biology