11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis
C. T. Davidson, E. Miller, M. Muir, J. C. Dawson, M. Lee, S. Aitken, A. Serrels, S. P. Webster, N. Z. M. Homer, R. Andrew, V. G. Brunton, P. W. F. Hadoke, B. R. Walker
This study investigates the effect of 11β-HSD1 inhibition on tumour growth and angiogenesis in murine models, finding increased SCC tumour growth but no effect on angiogenesis.
bioRxiv · Aug 4, 2021 · PreprintCancer Biology