Cancer BiologybioRxiv
PCK2 opposes mitochondrial respiration and maintains the redox balance in starved lung cancer cells
K. Leithner, G. Grasmann, M. Planque…·H. Olschewski
This study shows PCK2 regulates mitochondrial respiration and redox balance in starved lung cancer cells by modulating TCA cycle intermediates and glutathione oxidation.
DOI 10.1016/j.freeradbiomed.2021.09.007