Author

A. A. Peden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Firth· 1 shared C. T. Madreiter-Sokolowski· 1 shared D. E. Gordon· 1 shared D. M. Williams· 1 shared D. Seiler· 1 shared G. W. Carnell· 1 shared H. K. Jackson· 1 shared H. Stewart· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. Firth

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Author profile →

3 papers

Recent·Most cited

S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

D. M. Williams, A. A. Peden

This study shows that S-acylation of NLRP3's Cys-130 residue regulates its Golgi association through a nigericin-sensitive cycle, linking Golgi dysfunction to NLRP3 activation.

bioRxiv · Nov 14, 2023Cell Biology

Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

H. Stewart, R. Palmulli, K. H. Johansen, N. McGovern, O. M. Shehata, G. W. Carnell, H. K. Jackson, J. S. Lee, J. C. Brown, T. C. Burgoyne, J. L. Heeney, K. Okkenhaug, A. Firth, A. A. Peden, J. R. Edgar

This study shows SARS-CoV-2 evades tetherin restriction by multiple mechanisms, including ORF3a disrupting tetherin localization and Spike protein reducing tetherin levels, enhancing viral release.

bioRxiv · Jan 6, 2021Cell Biology

ALG-2 And Peflin Stimulate or Inhibit COPII Targeting And Secretion In Response To Calcium Signaling

J. Sargeant, D. Seiler, T. Costain, C. T. Madreiter-Sokolowski, D. E. Gordon, A. A. Peden, R. Malli, W. F. Graier, J. C. Hay

This study shows ALG-2 and peflin regulate COPII-mediated ER-to-Golgi transport by modulating secretion rates in response to calcium signaling.

bioRxiv · Feb 22, 2020Cell Biology