M. Hernandez

Carboxydovores from the Pseudomonadota colonise volcanic soils during succession

This study isolates and characterizes two carboxydovore strains from volcanic soils, revealing differences in their CO oxidation mechanisms and proposing a new species.

Dictyostelium discoideum-assisted pharmacognosy of plant resources for discovering antivirulence molecules targeting Klebsiella pneumoniae

This paper uses Dictyostelium discoideum to screen plant extracts for antivirulence molecules targeting Klebsiella pneumoniae, identifying a methanolic root extract with 24 potential compounds.

Antimicrobial resistance in Arctic soils is mediated by competition and facilitation

The paper examines how antimicrobial resistance varies in Arctic soils and identifies competition and facilitation as key drivers of its spatial and temporal spread.

Effects of Polyphosphate metabolism Mutations on Biofilm, Capsule Formation and Virulence Traits in Hypervirulent ST23 Klebsiella pneumoniae SGH10

This study examines how mutations in polyphosphate metabolism affect biofilm, capsule formation, and virulence in hypervirulent Klebsiella pneumoniae using a model host.

Identification of diverse antibiotic resistant bacteria in agricultural soil with H218O stable isotope probing and metagenomics

This study identifies antibiotic-resistant bacteria in agricultural soil using stable isotope probing and metagenomics, revealing diverse ARGs in heavy fractions.

Extra-cellular matrix remodeling as a unique mechanism of expansion of periprostatic adipose tissue: a potential driver of prostate cancer aggressiveness

The paper defines abundant periprostatic adipose tissue using a statistical approach and shows it is associated with prostate cancer aggressiveness through extracellular matrix remodeling.

An Experimental Analysis of the Fine-Scale Effects of Nest Ectoparasites on Incubation Behavior

This study manipulates nest ectoparasites in barn swallows to examine their impact on incubation behavior and egg temperatures, finding that other factors drive most variation in incubation, but parasitized nests had warmer eggs with lower hatching success.

Wnt/PCP signaling mediates breast cancer metastasis by promoting pro-invasive protrusion formation in collectively motile leader cells

This study shows Wnt/PCP signaling promotes breast cancer metastasis by enhancing pro-invasive protrusions in leader cells during collective migration.

Generation of functional ciliates cholangiocytes from human pluripotent stem cells

This study generates functional cholangiocytes from human pluripotent stem cells that exhibit mature characteristics and can be used for drug testing and disease modeling.

Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection

This paper develops a multiplex immunoassay to measure SARS-CoV-2 antibody responses and finds that severe COVID-19 is associated with higher early antibody levels against S1 and N proteins.

Disproportionate CH4 sink strength from an endemic, sub-alpine Australian soil microbial community

The paper measures methane fluxes and microbial communities in different soil types to show forest soils are strong CH4 sinks while bogs are sources, highlighting the role of specific methanotrophs.

Resuscitation of soil microbiota after > 70-years of desiccation

This study assesses bacterial abundance and diversity in 70-year-old desiccated soils, showing significant resuscitation potential and activity of certain taxa after rewetting.

Reconstructing genomes of carbon monoxide oxidisers in volcanic deposits including members of the class Ktedonobacteria

The paper reconstructs genomes of carbon monoxide oxidizers in Chilean volcanic soils, identifying Ktedonobacteria as potential CO utilizers in these environments.

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19

This study develops a human lung organoid model to emulate COVID-19 pathogenesis, showing proximal airway cells drive viral infection while distal cells drive excessive immune response.

Mobilization of a Kluyvera-like arnBCADTEF operon, besides mcr genes, confers colistin resistance to Escherichia coli isolated from healthy animals

This study identifies mobilization of a Kluyvera-like arnBCADTEF operon as a new colistin resistance mechanism in E. coli from healthy animals, alongside mcr genes and chromosomal mutations.

Resourceful mice do not starve: feeding efforts and decision-making process under a restricted unknown food source

The paper investigates how wild mice adjust feeding efforts and decision-making when faced with a novel food source under varying predation risk and experience conditions.

New insights of the local immune response against both fertile and infertile hydatid cysts

The paper investigates immune infiltration in fertile and infertile hydatid cysts, finding that immune cells disrupt the laminated layer in infertile cysts, potentially causing infertility.