Author

C. W. G. Fishwick

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. A. Cole· 1 shared H. Dejakaisaya· 1 shared J. D. Lippiat· 1 shared N. Pilati· 1 shared R. M. Johnson· 1 shared S. P. Muench· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. A. Cole

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1 paper

Recent·Most cited

Structure-based identification and characterisation of novel inhibitors of KNa1.1 potassium channels, a stratified target for KCNT1-related epilepsy.

B. A. Cole, R. M. Johnson, H. Dejakaisaya, N. Pilati, C. W. G. Fishwick, S. P. Muench, J. D. Lippiat

This study identifies novel inhibitors of KNa1.1 potassium channels using cryo-EM structures and computational methods, showing improved potency over quinidine for KCNT1-related epilepsy treatment.

bioRxiv · Sep 26, 2019Pharmacology & Toxicology