Author

C. W. M. Ong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. Bai· 2 shared C. S. L. Ding· 2 shared J. M. Hong· 2 shared P. M. Thong· 2 shared Q. H. Miow· 2 shared R. Rajarethinam· 2 shared X. Y. Poh· 2 shared Y. Wang· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

C. Bai

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2 papers

Recent·Most cited

PathologybioRxivPreprintOct 5, 2023

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai…·C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

DOI 10.1101/2023.10.05.561002

MicrobiologybioRxivAug 15, 2021

Nos2-/- mice infected with M. tuberculosis develop neurobehavioral changes and immunopathology mimicking human central nervous system tuberculosis

X. Y. Poh, J. M. Hong, C. Bai…·C. W. M. Ong

This study develops a murine model of CNS-TB using Nos2-/- mice infected with M. tuberculosis, showing neurobehavioral changes and immunopathology similar to human CNS-TB.

DOI 10.1186/s12974-022-02387-0

mouseexperimental assay