Author

R. Rajarethinam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Bai· 2 shared C. S. L. Ding· 2 shared C. W. M. Ong· 2 shared J. M. Hong· 2 shared P. M. Thong· 2 shared Q. H. Miow· 2 shared X. Y. Poh· 2 shared Y. Wang· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

C. Bai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai, H. T. Chong, W. K. Teo, J. M. Hong, Q. H. Miow, P. M. Thong, B. Vilaysane, T. H. Hu, S. Chhabra, Y. Wang, S. C. Tiong, S. M. Fong, M. Kamihigashi, , C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

bioRxiv · Oct 5, 2023 · PreprintPathology

Nos2-/- mice infected with M. tuberculosis develop neurobehavioral changes and immunopathology mimicking human central nervous system tuberculosis

X. Y. Poh, J. M. Hong, C. Bai, Q. H. Miow, P. M. Thong, Y. Wang, R. Rajarethinam, C. S. L. Ding, C. W. M. Ong

This study develops a murine model of CNS-TB using Nos2-/- mice infected with M. tuberculosis, showing neurobehavioral changes and immunopathology similar to human CNS-TB.

bioRxiv · Aug 15, 2021Microbiology

Trimester-specific Zika virus infection affects placental responses in women

F. M. Lum, V. Narang, S. Hue, C. Jie, N. McGovern, R. Rajarethinam, J. Tan, S. N. Amrun, Y. H. Chan, C. Y. P. Lee, T. K. Chua, W. X. Yee, N. K. W. Yeo, T. C. Tan, L. Xuan, , L. Ng

This study examines how ZIKV infection during different pregnancy trimesters affects placental immune and transcriptomic responses, identifying unique molecular changes associated with early infection.

bioRxiv · Aug 6, 2019 · PreprintImmunology