Mechanistic of Rac and Cdc42 synchronization at the cell edge by ARHGAP39-dependent signaling nodules and the impact on protrusion dynamics
M. Howell, V. Delorme-Walker, C. Welch, R. Pathak, K. M. Hahn, C. DerMardirossian
This study identifies ARHGAP39's role in synchronizing Rac and Cdc42 activity at the cell edge through signaling nodules, impacting protrusion dynamics and cell invasion.
bioRxiv · May 13, 2021 · PreprintCell Biology