Inside-out regulation of E-cadherin conformation and adhesion
R. Koirala, A. V. Priest, C.-F. Yen, J. S. Cheah, W.-J. Pannekoek, M. Gloerich, S. Yamada, S. Sivasankar
This study shows vinculin regulates cadherin conformation and adhesion by converting weak X-dimers to strong strand-swap dimers through myosin II-dependent cytoskeletal tension changes.
bioRxiv · May 2, 2020Biophysics