C.-W. Chu

Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors

This study shows that PD-1 glycosylation variants affect the efficacy of immune checkpoint inhibitors and suggests personalized therapeutic approaches.

Myosin-dependent partitioning of junctional Prickle2 toward the anterior vertex during planar polarization of Xenopus neuroectoderm

This study shows that NMII activity drives anterior movement of Pk2 toward the anterior vertex by regulating junction dynamics during Xenopus neuroectoderm planar polarization.

Lmo7 recruits myosin II heavy chain to induce apical constriction in Xenopus ectoderm

This study identifies Lmo7 as a scaffold that recruits myosin II to apical junctions, promoting apical constriction in Xenopus ectoderm.