Nilotinib activates endothelial TLR4 to exacerbate atherosclerosis
D. Qu, M. Huo, L. Wang, C.-W. Lau, X. Y. Tian, Y. Huang
This study shows nilotinib activates endothelial TLR4, promoting atherosclerosis, and suggests TLR4 inhibition could mitigate this effect.
bioRxiv · Dec 14, 2019 · PreprintCell Biology