Enriched environment requires remodeling of hippocampal perineuronal nets to trigger memory improvement in Alzheimer's mouse model
Guillaume Bouisset, Fanny J. Tixier, Tatiana Dupak, Camille Lejards, Laure Verret
This study shows that enriched environments improve memory in Alzheimer's mice by remodeling hippocampal perineuronal nets, and that blocking this remodeling prevents memory recovery.
iScience · Aug 12, 2025Peer-reviewedNeuroscience