Axon-secreted chemokine-like Orion is a signal for astrocyte infiltration during neuronal remodeling
Ana Boulanger, Camille Thinat, Stephan L. Zuchner, Lee G. Fradkin, Hugues Lortat‐Jacob, Jean‐Maurice Dura
The paper identifies a new gene, orion, which is secreted by neurons and recruits astrocytes for axon pruning and debris removal during neuronal remodeling in Drosophila.
bioRxiv · Nov 23, 2020 · PreprintNeuroscience